U.S. stocks lower at close of trade; Dow Jones Industrial Average down 0.38% By Investing.com

Investing.com – U.S. stocks were lower after the close on Friday, as losses in the , and sectors led shares lower.

At the close in NYSE, the fell 0.38%, while the index lost 1.04%, and the index fell 1.59%.

The best performers of the session on the were American Express Company (NYSE:), which rose 3.32% or 5.74 points to trade at 178.87 at the close. Meanwhile, Apple Inc (NASDAQ:) added 2.44% or 3.68 points to end at 154.50 and JPMorgan Chase & Co (NYSE:) was up 1.51% or 2.10 points to 141.04 in late trade.

The worst performers of the session were Home Depot Inc (NYSE:), which fell 2.45% or 8.31 points to trade at 331.48 at the close. Microsoft Corporation (NASDAQ:) declined 2.36% or 6.26 points to end at 258.35 and 3M Company (NYSE:) was down 2.31% or 2.78 points to 117.51.

The top performers on the S&P 500 were Clorox Co (NYSE:) which rose 9.77% to 154.78, Regeneron Pharmaceuticals Inc (NASDAQ:) which was up 4.25% to settle at 783.13 and Church & Dwight Company Inc (NYSE:) which gained 3.86% to close at 82.89.

The worst performers were Gen Digital Inc (NASDAQ:) which was down 9.63% to 21.30 in late trade, MarketAxess Holdings Inc (NASDAQ:) which lost 8.96% to settle at 345.90 and Amazon.com Inc (NASDAQ:) which was down 8.43% to 103.39 at the close.

The top performers on the NASDAQ Composite were ReShape Lifesciences Inc (NASDAQ:) which rose 170.48% to 17.04, Heart Test Laboratories Inc Unit (NASDAQ:) which was up 139.44% to settle at 3.40 and Genetic Technologies Ltd (NASDAQ:) which gained 80.20% to close at 1.82.

The worst performers were Gaucho Group Holdings Inc (NASDAQ:) which was down 46.11% to 2.91 in late trade, Edible Garden AG Inc (NASDAQ:) which lost 43.11% to settle at 4.75 and MDxHealth SA ADR (NASDAQ:) which was down 38.06% to 3.89 at the close.

Falling stocks outnumbered advancing ones on the New York Stock Exchange by 2184 to 849 and 80 ended unchanged; on the Nasdaq Stock Exchange, 2238 fell and 1450 advanced, while 158 ended unchanged.

Shares in Regeneron Pharmaceuticals Inc (NASDAQ:) rose to all time highs; up 4.25% or 31.93 to 783.13. Shares in Heart Test Laboratories Inc Unit (NASDAQ:) rose to all time highs; up 139.44% or 1.98 to 3.40. Shares in MDxHealth SA ADR (NASDAQ:) fell to all time lows; down 38.06% or 2.39 to 3.89.

The , which measures the implied volatility of S&P 500 options, was down 2.14% to 18.33.

Gold Futures for April delivery was down 2.70% or 52.05 to $1,878.75 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in March fell 3.43% or 2.60 to hit $73.28 a barrel, while the April Brent oil contract fell 2.88% or 2.37 to trade at $79.80 a barrel.

EUR/USD was down 1.01% to 1.08, while USD/JPY rose 1.97% to 131.18.

The US Dollar Index Futures was up 1.20% at 102.79.